CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    Minyard A

    Mutations:

    Mutant Gene Virus Reference
    Q167R UL27 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    L317V UL27 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    A375T UL27 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    N498S UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    N498S UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    N498S UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    D515E UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    D515E UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    D515E UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    D542E UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    D542E UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    D542E UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    A543V UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    A543V UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    A543V UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    A786V UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    A786V UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    A786V UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    A928T UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    A928T UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    A928T UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    E949K UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    E949K UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    E949K UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    E949Q UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    E949Q UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    E949Q UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    D981del2 UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    D981del2 UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    D981del2 UL54 Human betaherpesvirus 5 A new locus of foscarnet resistance in the cytomegalovirus UL54 DNA polymerase gene among uncharacterized mutations in recent clinical trials. (Feb 2026)
    T400M UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    T400M UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    A543T UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    A543T UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    R570Q UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    R570Q UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    A591V UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    G598A UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    G598A UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    K599N UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    K599N UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    L622M UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    L622M UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    P706S UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    P706S UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    Q381del2 UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)
    Q381del2 UL97 Human betaherpesvirus 5 Low level drug resistance linked to cytomegalovirus UL97 and UL27 mutations detected in maribavir clinical trials. (Sep 2026)


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230