Codex_V5

A594T

Antiviral	EC50 ratio	Phenotype	Strain	Source	Marker	Assay	Reference
Ganciclovir	5.00	High level resistance		Laboratory strain, Clinical Isolate	Recombinant	Details	Antiviral susceptibilities and analysis of UL97 and DNA polymerase sequences of clinical cytomegalovirus isolates from immunocompromised patients. (May 1997)
Maribavir	0.73	No resistance		Laboratory strain, Clinical Isolate	Recombinant	Details	Antiviral susceptibilities and analysis of UL97 and DNA polymerase sequences of clinical cytomegalovirus isolates from immunocompromised patients. (May 1997)

Mutant	Resistances
A594E	Ganciclovir: Intermediate level resistance
A594G	Ganciclovir: High level resistance
A594P	Ganciclovir: High level resistance
A594P	Maribavir: No resistance
A594S	Ganciclovir: Range of values between Low level resistance and Intermediate level resistance
A594V	Filociclovir: Range of values between Low level resistance and Intermediate level resistance
A594V	Maribavir: No resistance
A594V	Ganciclovir: High level resistance