Codex_V5

A594G

Antiviral	EC50 ratio	Phenotype	Strain	Source	Marker	Assay	Reference
Ganciclovir	13.50	High level resistance		Laboratory strain, Clinical Isolate	Recombinant	Details	Value of a ligase chain reaction assay for detection of ganciclovir resistance-related mutation 594 in UL97 gene of human cytomegalovirus. (Sep 1997)

Mutant	Resistances
A594E	Ganciclovir: Intermediate level resistance
A594P	Ganciclovir: High level resistance
A594P	Maribavir: No resistance
A594S	Ganciclovir: Range of values between Low level resistance and Intermediate level resistance
A594T	Ganciclovir: High level resistance
A594T	Maribavir: No resistance
A594V	Filociclovir: Range of values between Low level resistance and Intermediate level resistance
A594V	Maribavir: No resistance
A594V	Ganciclovir: High level resistance