CHARMD
Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database
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Last update : Mon 20 Apr 2026
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Measure details
Mutant:
A594T
Gene:
UL97
Virus:
Human betaherpesvirus 5
Strain:
Reference:
Antiviral susceptibilities and analysis of UL97 and DNA polymerase sequences of clinical cytomegalovirus isolates from immunocompromised patients. (May 1997)
Antiviral:
Ganciclovir
EC50 ratio: 5.00
Phenotype: High level resistance
Passage: N/A
Source: Laboratory strain, Clinical Isolate
Marker: Recombinant
Details:
PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer
Observations:
Autre publi ID : update 2024 9129070, 19063923 15230476 11807689 9207351 10443790 11740736 11704031 23375740 Mutation update 2024 9129070, fr?quemment retrouv?e chez les patients re?evant des CS h?matopo?etiques
Tilloy
et al.
, 2024
Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230