Codex_V5

A594E

Antiviral	EC50 ratio	Phenotype	Strain	Source	Marker	Assay	Reference
Ganciclovir	3.00	Intermediate level resistance		Laboratory strain, Clinical Isolate	Recombinant	Details	Cytomegalovirus UL97 phosphotransferase mutations that affect susceptibility to ganciclovir. (Jan 2002)

Mutant	Resistances
A594G	Ganciclovir: High level resistance
A594P	Ganciclovir: High level resistance
A594P	Maribavir: No resistance
A594S	Ganciclovir: Range of values between Low level resistance and Intermediate level resistance
A594T	Ganciclovir: High level resistance
A594T	Maribavir: No resistance
A594V	Filociclovir: Range of values between Low level resistance and Intermediate level resistance
A594V	Maribavir: No resistance
A594V	Ganciclovir: High level resistance