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Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database
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Last update : Mon 20 Apr 2026
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Measure details
Mutant:
A594G
Gene:
UL97
Virus:
Human betaherpesvirus 5
Strain:
Reference:
Value of a ligase chain reaction assay for detection of ganciclovir resistance-related mutation 594 in UL97 gene of human cytomegalovirus. (Sep 1997)
Antiviral:
Ganciclovir
EC50 ratio: 13.50
Phenotype: High level resistance
Passage: N/A
Source: Laboratory strain, Clinical Isolate
Marker: Recombinant
Details:
PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer
Observations:
Autre publi ID : 31940472
Tilloy
et al.
, 2024
Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230