Codex_V5

Bowlin TL

References:

Rank: 2 - Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility.(Jan 2011)
Rank: 3 - Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure.(Jan 2012)
Rank: 4 - Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance.(Jul 2013)
Rank: 10 - Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions.( 2014)

Mutations:

Mutant	Gene	Virus	Reference
M844T	UL54	Human betaherpesvirus 5	Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
M844T	UL54	Human betaherpesvirus 5	Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
M844T	UL54	Human betaherpesvirus 5	Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
M844V	UL54	Human betaherpesvirus 5	Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
M844V	UL54	Human betaherpesvirus 5	Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
M844V	UL54	Human betaherpesvirus 5	Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
F342S	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
F342S	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
K355del	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
K355del	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
V356G	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
V356G	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
D456N	UL97	Human betaherpesvirus 5	Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions. ( 2014)
D456N	UL97	Human betaherpesvirus 5	Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions. ( 2014)
M460I	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility. (Jan 2011)
M460V	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility. (Jan 2011)
V466G	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
C480R	UL97	Human betaherpesvirus 5	Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions. ( 2014)
C480R	UL97	Human betaherpesvirus 5	Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions. ( 2014)
H520Q	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility. (Jan 2011)
P521L	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
P521L	UL97	Human betaherpesvirus 5	Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
Y617del	UL97	Human betaherpesvirus 5	Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions. ( 2014)
Y617del	UL97	Human betaherpesvirus 5	Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions. ( 2014)