CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    D456N

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Maribavir 278.00 High level resistance Laboratory strain Recombinant Details Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions. ( 2014)
    Ganciclovir 12.00 High level resistance Laboratory strain Recombinant Details Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions. ( 2014)


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230