Antiviral | EC50 ratio | Phenotype | Strain | Source | Marker | Assay | Reference |
---|---|---|---|---|---|---|---|
Filociclovir | 4.00 | Intermediate level resistance | Laboratory strain | Recombinant | Details | Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility. (Jan 2011) | |
Maribavir | 0.30 | Possible hypersensitivity, no resistance | Laboratory strain | Recombinant | Details | Ganciclovir and maribavir cross-resistance revisited: Relative drug susceptibilities of canonical cytomegalovirus mutants. (Feb 2024) | |
Ganciclovir | 9.10 | High level resistance | Recombinant | Recombinant | Details | Ganciclovir and maribavir cross-resistance revisited: Relative drug susceptibilities of canonical cytomegalovirus mutants. (Feb 2024) |
Mutant | Resistances |
---|---|
M460I |
Filociclovir:
|
M460I |
Maribavir:
|
M460I |
Ganciclovir:
|
M460L |
|
M460T |
Ganciclovir:
|