CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    M844T

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 1.40 No resistance N/A N/A N/A Details Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
    Cidofovir 1.30 No resistance N/A N/A N/A Details Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
    Foscarnet 2.50 Low level resistance N/A N/A N/A Details Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)

    Mutations at the same locus:

    Mutant Resistances
    M844V Ganciclovir: Low level resistance
    Cidofovir: No resistance
    Foscarnet: Low level resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230