Herpesvirus Antiviral Resistance
Database


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    M844T

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 1.40 No resistance Details Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
    Cidofovir 1.30 No resistance Details Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
    Foscarnet 2.50 Low level resistance Details Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)

    Mutations at the same locus:

    Mutant Resistances
    M844V Ganciclovir: Low level resistance
    M844V Cidofovir: No resistance
    M844V Foscarnet: Low level resistance