CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    M844V

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 2.50 Low level resistance Details Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
    Cidofovir 1.60 No resistance Details Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
    Foscarnet 2.20 Low level resistance Details Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)

    Mutations at the same locus:

    Mutant Resistances
    M844T Ganciclovir: No resistance
    M844T Cidofovir: No resistance
    M844T Foscarnet: Low level resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230