CHARMD
Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database
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Last update : Mon 20 Apr 2026
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Marousek G
References:
Rank: 2 -
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease.(Sep 1997)
Rank: 2 -
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus.(Sep 2008)
Rank: 2 -
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure.(Jan 2012)
Rank: 2 -
Recombinant phenotyping of cytomegalovirus sequence variants detected after 200 or 100 days of valganciclovir prophylaxis.(Dec 2010)
Rank: 3 -
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance.(Jul 2013)
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Mutant
Gene
Virus
Reference
Mutations:
F412C
UL54
Human betaherpesvirus 5
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. (Sep 1997)
F412C
UL54
Human betaherpesvirus 5
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. (Sep 1997)
F412C
UL54
Human betaherpesvirus 5
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. (Sep 1997)
I521T
UL54
Human betaherpesvirus 5
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. (Sep 2008)
I521T
UL54
Human betaherpesvirus 5
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. (Sep 2008)
I521T
UL54
Human betaherpesvirus 5
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. (Sep 2008)
P522L
UL54
Human betaherpesvirus 5
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. (Sep 2008)
P522A
UL54
Human betaherpesvirus 5
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. (Sep 2008)
P522A
UL54
Human betaherpesvirus 5
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. (Sep 2008)
P522A
UL54
Human betaherpesvirus 5
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. (Sep 2008)
L802M
UL54
Human betaherpesvirus 5
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. (Sep 1997)
L802M
UL54
Human betaherpesvirus 5
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. (Sep 1997)
L802M
UL54
Human betaherpesvirus 5
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. (Sep 1997)
M844T
UL54
Human betaherpesvirus 5
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
M844T
UL54
Human betaherpesvirus 5
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
M844T
UL54
Human betaherpesvirus 5
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
M844V
UL54
Human betaherpesvirus 5
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
M844V
UL54
Human betaherpesvirus 5
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
M844V
UL54
Human betaherpesvirus 5
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. (Jan 2012)
F342S
UL97
Human betaherpesvirus 5
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
F342S
UL97
Human betaherpesvirus 5
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
K355del
UL97
Human betaherpesvirus 5
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
K355del
UL97
Human betaherpesvirus 5
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
V356G
UL97
Human betaherpesvirus 5
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
V356G
UL97
Human betaherpesvirus 5
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
A440V
UL97
Human betaherpesvirus 5
Recombinant phenotyping of cytomegalovirus sequence variants detected after 200 or 100 days of valganciclovir prophylaxis. (Dec 2010)
A442G
UL97
Human betaherpesvirus 5
Recombinant phenotyping of cytomegalovirus sequence variants detected after 200 or 100 days of valganciclovir prophylaxis. (Dec 2010)
V466G
UL97
Human betaherpesvirus 5
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
P521L
UL97
Human betaherpesvirus 5
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
P521L
UL97
Human betaherpesvirus 5
Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance. (Jul 2013)
Tilloy
et al.
, 2024
Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230