CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    L802M

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 1.10-3.50 Range of values between No resistance and Intermediate level resistance Recombinant Details Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. (Sep 1997)
    Cidofovir 0.90-1.80 Range of values of No resistance Recombinant Details Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. (Sep 1997)
    Foscarnet 3.20-10.80 Range of values between Intermediate level resistance and High level resistance Recombinant Details Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. (Sep 1997)

    Mutations at the same locus:

    Mutant Resistances
    L802V Ganciclovir: No resistance
    L802V Cidofovir: No resistance
    L802V Foscarnet: No resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230