Codex_V5

Recombinant phenotyping of cytomegalovirus sequence variants detected after 200 or 100 days of valganciclovir prophylaxis.

Pubmed_id: 21030903
Journal: Transplantation
Genbank_id: No known Genbank_id
Date: Dec 2010
Volume: 90
Issue: 12
Pages: 1409-13
Author(s): Chou S, Marousek G, Boivin G, Goyette N, Farhan M, Ives JA, Elston R,

Abstract: Phenotypic evaluation of previously uncharacterized viral genotypes in the 200-day valganciclovir prophylaxis group showed no evidence of an increased incidence of genotypic ganciclovir resistance when compared with those in the 100-day prophylaxis group.

Mutant	Gene	Virus	Antiviral	EC50 ratio	Phenotype
A440V	UL97	Human betaherpesvirus 5			Natural polymorphism
A442G	UL97	Human betaherpesvirus 5			Natural polymorphism