CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    C592F

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 31.50 High level resistance Laboratory strain, Clinical Isolate Recombinant Details Aciclovir selects for ganciclovir-cross-resistance of human cytomegalovirus in vitro that is only in part explained by known mutations in the UL97 protein. (Sep 2001)

    Mutations at the same locus:

    Mutant Resistances
    C592G Filociclovir: Range of values between Low level resistance and Intermediate level resistance
    C592G Maribavir: No resistance
    C592G Ganciclovir: Intermediate level resistance
    C592G Ganciclovir: Intermediate level resistance
    C592G Ganciclovir: Intermediate level resistance
    C592G Ganciclovir: Intermediate level resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230