CHARMD

TOP

• Mutant: C592F
• Gene: UL97
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Aciclovir selects for ganciclovir-cross-resistance of human cytomegalovirus in vitro that is only in part explained by known mutations in the UL97 protein. (Sep 2001)


• Antiviral: Ganciclovir
• EC50 ratio: 31.50
• Phenotype: High level resistance
• Passage: N/A
• Source: Laboratory strain, Clinical Isolate
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • No observations associated