Antiviral | EC50 ratio | Phenotype | Strain | Source | Marker | Assay | Reference |
---|---|---|---|---|---|---|---|
Ganciclovir | 3.80 | Intermediate level resistance | Recombinant | Details | How evolution of mutations conferring drug resistance affects viral dynamics and clinical outcomes of cytomegalovirus-infected hematopoietic cell transplant recipients. (Jan 2005) | ||
Cidofovir | 2.70 | Low level resistance | Recombinant | Details | How evolution of mutations conferring drug resistance affects viral dynamics and clinical outcomes of cytomegalovirus-infected hematopoietic cell transplant recipients. (Jan 2005) | ||
Foscarnet | 3.20-9.00 | Range of values between Intermediate level resistance and High level resistance | Recombinant | Details | How evolution of mutations conferring drug resistance affects viral dynamics and clinical outcomes of cytomegalovirus-infected hematopoietic cell transplant recipients. (Jan 2005) |
Mutant | Resistances |
---|---|
D588E |
Ganciclovir:
|
D588E |
Cidofovir:
|
D588E |
Foscarnet:
|