Antiviral | EC50 ratio | Phenotype | Strain | Source | Marker | Assay | Reference |
---|---|---|---|---|---|---|---|
Ganciclovir | 3.70 | Intermediate level resistance | Recombinant | Details | Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing. (Aug 2014) | ||
Cidofovir | 10.00 | High level resistance | Recombinant | Details | Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing. (Aug 2014) | ||
Foscarnet | 1.10 | No resistance | Recombinant | Details | Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing. (Aug 2014) |
Mutant | Resistances |
---|---|
K513E |
Ganciclovir:
|
K513E |
Cidofovir:
|
K513E |
Foscarnet:
|
K513N |
Ganciclovir:
|
K513N |
Cidofovir:
|
K513N |
Foscarnet:
|
K513Q |
Ganciclovir:
|
K513Q |
Cidofovir:
|
K513Q |
Foscarnet:
|