| Antiviral | EC50 ratio | Phenotype | Strain | Source | Marker | Assay | Reference |
|---|---|---|---|---|---|---|---|
| Ganciclovir | 5.00 | High level resistance | Recombinant | Details | Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998) | ||
| Cidofovir | 9.10 | High level resistance | Recombinant | Details | Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998) | ||
| Foscarnet | 1.40 | No resistance | Recombinant | Details | Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998) |
| Mutant | Resistances |
|---|---|
| K513N |
Ganciclovir:
|
| K513N |
Cidofovir:
|
| K513N |
Foscarnet:
|
| K513Q |
Ganciclovir:
|
| K513Q |
Cidofovir:
|
| K513Q |
Foscarnet:
|
| K513R |
Ganciclovir:
|
| K513R |
Cidofovir:
|
| K513R |
Foscarnet:
|