Patrick Trouillas

Prof.

+33(0)5 19 56 42 51

About me...

H-index: 23 

ORCID: 

ResearcherID: 

  • Since 2016: Professor – Faculty of Pharmacy (University of Limoges – France)
  • Since 2013: Researcher at INSERM U1248 (Pharmacology of immunosuppressant drugs in transplantation) (Limoges – France)
  • Since 2013: Associate Researcher at Regional Center of Advanced Technologies and Materials (Olomouc – Czech Republic) 
  • 1997-2016: Associate Professor – Faculty of Pharmacy (University of Limoges – France)
  • 1996-1997: Post-Doc in the Laboratory for Optical Materials (CEA) in Tours (France)
  • 1992-1996: PhD at the University of Limoges (Faculty of Sciences) Limoges (France) 

Awards

  • 2014: Award of the best foreigner scientist (2014) of RCPTM (Czech Rep.)
  • 2002: National Reward for Scientific Excellence (from 2002)
  • 2001: Young Investigator Award, International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT)
  • 2009: C.E. Pippenger Award for outstanding contributions to Therapeutic Drug Monitoring (IATDMCT) 

 Invited Conferences

  • Invited conferences (12) + several national & international seminars, oral communications (personal or supervised PhD students)

Positions in Learned Societies

  • Member of 4 European COST programs (CM0804, FA1003, CM1004) + Erasmus and Hubert Curien programs

National and International Network 

  • EU Network RCPTM (Olomouc – Czech Rep.)
  • LCMN (Mons – Belgium)
  • Institut für Chemie, Technische Universität Berlin
 (Berlin, Germany)
  • Dpt of Physical Chemistry (Alicante, Spain)
  • Faculty of Medicine (Olomouc – Czech Republic)
  • Academy of Sciences (Prague – Czech Rep.)
  • IMDEA in Nanoscience (Madrid, Spain)
  • Univ. Avignon, INRA (Avignon, France)
  • Univ. Riga & Latvian State Institute of Wood Chemistry (Riga, Latvia)
  • Univ. Szeged (Szeged, Hungary).

Others

  • Reviewers for many international journals 1<IF<12
  • Invited Professor at the University of Mons (Belgium) [2006, 2009-2013, 2016]
  • 2008 Qualification as Professor (section 31 – Theoretical Chemistry & Physics)
  • 2004 HDR – Accreditation to supervise research “Chatting with quantum entities of natural antioxidants” Limoges
  • 1996 PhD “C60: from the origin of their electronic and optical properties to its behavior under ion beams” Limoges
  • Language French: Mother Tongue; English: daily use + good working knowledge (Medical English Diploma in 2005)

Supervision

  • Supervisor of 3 Post-Doc + 11 PhD students + several Masters; Examination board for several PhDs

Teaching

  • Biophysics, Physical Chemistry and Molecular Modeling for students in Biology & Pharmacy (~200 h per a year)
  • Activity leader in the Scientibus (http://www.unilim.fr/scientibus/)
  • Since 2009: Scientific evaluator for the Belgian FNRS and French National Research Committees
  • Since 2009: Member of the managing committee of the European COST action 0804
  • Since 2007: Member of the scientific committee of the supercomputer CALI in Limoges; project manager for computational facility proposals to the National Institute for Development and Resources in Intensive Scientific computing.
  • Since 2001: Member of committees for lecturer selection
  • 1999-2013: Member of the “Conseil National des Universités” (CNU – section 85)

RESEARCH ACTIVITIES

2013-nowadays:

  • Molecular Dynamics (MD) simulations of membrane crossing (permeation and active transport) by natural & bio-inspired antioxidants, and drugs of transplantation: towards in silico pharmacology
  • Antioxidants in cosmetics and organ transplantation (prevention of ischemia-reperfusion): theoretical approaches
  • Molecular & supramolecular (noncovalent) arrangements: towards understanding chemistry and biological (antioxidant) activities.

2000-nowadays

  • Development of a molecular modelling unit at the University of Limoges
  • Quantum chemical calculations to rationalize free radical biological events
  • Thermodynamics and kinetics of electron transfer and atom transfers of natural antioxidants
  • Pigmentation and copigmentation (π-stacking association by DFT-D, charge transfer UV-vis absorption spectra by TD-DFT). Theoretical evaluation of solvent effects: use of explicit or implicit (continuum-based) models
  • MD simulation of interactions between antioxidants and lipid bilayer membranes

1997-1999

  • Change in Thematic from Solid State Physics to Pharmaceutical problems
  • Experimental evaluations of antioxidant activities of natural compounds

1996-1997

  • Simulations (finite element) of thermic exchanges in multilayer structures exhibiting infrared furtivity properties

1992-1996

  • User of a particle accelerator HVEE 400kV / Deposition of fullerene C60 thin films / Measurements of electrical and optical properties of implanted C60 solids – Collaboration with the Cavendish Laboratory in Cambridge (UK)