CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    E989D

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Cidofovir 1.90 No resistance Clinical Isolate Details Drug Resistance Mutations and Associated Phenotypes Detected in Clinical Trials of Maribavir for Treatment of Cytomegalovirus Infection. (Sep 2022)
    Foscarnet 5.70 High level resistance Clinical Isolate Details Drug Resistance Mutations and Associated Phenotypes Detected in Clinical Trials of Maribavir for Treatment of Cytomegalovirus Infection. (Sep 2022)
    Ganciclovir 3.20 Intermediate level resistance Clinical Isolate Details Drug Resistance Mutations and Associated Phenotypes Detected in Clinical Trials of Maribavir for Treatment of Cytomegalovirus Infection. (Sep 2022)

    Mutations at the same locus:

    Mutant Resistances
    E989Q Natural polymorphism


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230