CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database

F460S

Virus: Human betaherpesvirus 5
Gene: UL54
Resistance summary:*
- Natural polymorphism

*If there is more than one line per antiviral, please refer to the table below

Antiviral assays:

Antiviral	EC50 ratio	Phenotype	Strain	Source	Marker	Assay	Reference
		Natural polymorphism				Details	Genotypic and Phenotypic Study of Antiviral Resistance Mutations in Refractory Cytomegalovirus Infection. (Nov 2022)

Mutations at the same locus:

Mutant	Resistances
F460L	Ganciclovir: No resistance
F460L	Cidofovir: No resistance
F460L	Foscarnet: No resistance

Tilloy et al., 2024

Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230