CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    C603R

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir Laboratory strain, Clinical Isolate Recombinant Details Analysis and characterization of antiviral drug-resistant cytomegalovirus isolates from solid organ transplant recipients. (Sep 2002)

    Mutations at the same locus:

    Mutant Resistances
    C603S Ganciclovir: No resistance
    C603W Filociclovir: Range of values between Low level resistance and Intermediate level resistance
    C603W Maribavir: No resistance
    C603W Ganciclovir: High level resistance
    C603Y Maribavir: No resistance
    C603Y Ganciclovir: Low level resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230