Herpesvirus Antiviral Resistance
Database


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    M460T

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 9.30 High level resistance Laboratory strain Recombinant Details Recombinant phenotyping of cytomegalovirus UL97 kinase sequence variants for ganciclovir resistance. (Jun 2010)

    Mutations at the same locus:

    Mutant Resistances
    M460I Filociclovir: High level resistance
    M460I Maribavir: Possible hypersensitivity, no resistance
    M460I Ganciclovir: High level resistance
    M460L
    M460V Filociclovir: Intermediate level resistance
    M460V Maribavir: Possible hypersensitivity, no resistance
    M460V Ganciclovir: High level resistance