Antiviral | EC50 ratio | Phenotype | Strain | Source | Marker | Assay | Reference |
---|---|---|---|---|---|---|---|
Ganciclovir | 2.50 | Low level resistance | Recombinant | Details | A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture. (Sep 1998) | ||
Cidofovir | 3.20 | Intermediate level resistance | Recombinant | Details | A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture. (Sep 1998) | ||
Foscarnet | 2.90 | Low level resistance | Recombinant | Details | A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture. (Sep 1998) | ||
Brincidofovir | 2.40 | Low level resistance | Laboratory strain | Recombinant | Details | Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance. (Jun 2016) |