Codex_V5

K805Q

Virus: Human betaherpesvirus 5
Gene: UL54
Resistance summary:*
- Ganciclovir: No resistance
- Cidofovir: Low level resistance
- Foscarnet: Possible hypersensitivity, no resistance

Antiviral	EC50 ratio	Phenotype	Marker	Assay	Reference
Ganciclovir	1.00	No resistance	Recombinant	Details	Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998)
Cidofovir	2.20	Low level resistance	Recombinant	Details	Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998)
Foscarnet	0.18	Possible hypersensitivity, no resistance	Recombinant	Details	Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998)