Herpesvirus Antiviral Resistance
Database


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    L802V

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 1.80 No resistance Recombinant Details Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet. (Sep 2011)
    Cidofovir 1.10 No resistance Recombinant Details Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet. (Sep 2011)
    Foscarnet 0.90 No resistance Recombinant Details Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet. (Sep 2011)

    Mutations at the same locus:

    Mutant Resistances
    L802M Ganciclovir: Range of values between No resistance and Intermediate level resistance
    L802M Cidofovir: Range of values of No resistance
    L802M Foscarnet: Range of values between Intermediate level resistance and High level resistance