CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    L802V

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 1.80 No resistance N/A N/A Recombinant Details Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet. (Sep 2011)
    Cidofovir 1.10 No resistance N/A N/A Recombinant Details Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet. (Sep 2011)
    Foscarnet 0.90 No resistance N/A N/A Recombinant Details Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet. (Sep 2011)

    Mutations at the same locus:

    Mutant Resistances
    L802M Ganciclovir: Range of values between No resistance and Intermediate level resistance
    Cidofovir: Range of values of No resistance
    Foscarnet: Range of values between Intermediate level resistance and High level resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230