Antiviral | EC50 ratio | Phenotype | Strain | Source | Marker | Assay | Reference |
---|---|---|---|---|---|---|---|
Ganciclovir | 2.40 | Low level resistance | Recombinant | Details | Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. (Mar 2003) | ||
Cidofovir | 1.00 | No resistance | Recombinant | Details | Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. (Mar 2003) | ||
Foscarnet | 4.10 | Intermediate level resistance | Recombinant | Details | Mutations conferring foscarnet resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis. (Mar 2003) |
Mutant | Resistances |
---|---|
V787A |
Ganciclovir:
|
V787A |
Cidofovir:
|
V787A |
Foscarnet:
|
V787E |
Ganciclovir:
|
V787E |
Cidofovir:
|
V787E |
Foscarnet:
|