Herpesvirus Antiviral Resistance
Database


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    V787E

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 8.60 High level resistance Details Compartmentalization of a Multidrug-Resistant Cytomegalovirus UL54 Mutant in a Stem Cell Transplant Recipient with Encephalitis. (Sep 2019)
    Cidofovir 2.90 Low level resistance Details Compartmentalization of a Multidrug-Resistant Cytomegalovirus UL54 Mutant in a Stem Cell Transplant Recipient with Encephalitis. (Sep 2019)
    Foscarnet 3.40 Intermediate level resistance Details Compartmentalization of a Multidrug-Resistant Cytomegalovirus UL54 Mutant in a Stem Cell Transplant Recipient with Encephalitis. (Sep 2019)

    Mutations at the same locus:

    Mutant Resistances
    V787A Ganciclovir: Low level resistance
    V787A Cidofovir:
    V787A Foscarnet: Intermediate level resistance
    V787L Ganciclovir: Low level resistance
    V787L Cidofovir: No resistance
    V787L Foscarnet: Intermediate level resistance