Antiviral | EC50 ratio | Phenotype | Strain | Source | Marker | Assay | Reference |
---|---|---|---|---|---|---|---|
Ganciclovir | 1.77 | No resistance | Recombinant | Details | Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance. (Jul 2016) | ||
Cidofovir | 0.47 | Possible hypersensitivity, no resistance | Recombinant | Details | Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance. (Jul 2016) | ||
Foscarnet | 2.50 | Low level resistance | Recombinant | Details | Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance. (Jul 2016) |
Mutant | Resistances |
---|---|
V715M |
Ganciclovir:
|
V715M |
Cidofovir:
|
V715M |
Foscarnet:
|