Herpesvirus Antiviral Resistance
Database


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    V715A

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 1.77 No resistance Recombinant Details Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance. (Jul 2016)
    Cidofovir 0.47 Possible hypersensitivity, no resistance Recombinant Details Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance. (Jul 2016)
    Foscarnet 2.50 Low level resistance Recombinant Details Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance. (Jul 2016)

    Mutations at the same locus:

    Mutant Resistances
    V715M Ganciclovir: No resistance
    V715M Cidofovir: No resistance
    V715M Foscarnet: High level resistance