Antiviral | EC50 ratio | Phenotype | Strain | Source | Marker | Assay | Reference |
---|---|---|---|---|---|---|---|
Ganciclovir | 4.90 | Intermediate level resistance | Recombinant | Details | Phenotypic diversity of cytomegalovirus DNA polymerase gene variants observed after antiviral therapy. (Apr 2011) | ||
Cidofovir | 6.30 | High level resistance | Recombinant | Details | Phenotypic diversity of cytomegalovirus DNA polymerase gene variants observed after antiviral therapy. (Apr 2011) | ||
Foscarnet | 1.30 | No resistance | Recombinant | Details | Phenotypic diversity of cytomegalovirus DNA polymerase gene variants observed after antiviral therapy. (Apr 2011) |
Mutant | Resistances |
---|---|
L545F |
Ganciclovir:
|
L545F |
Cidofovir:
|
L545F |
Foscarnet:
|
L545S |
Ganciclovir:
|
L545S |
Cidofovir:
|
L545S |
Foscarnet:
|