Antiviral | EC50 ratio | Phenotype | Strain | Source | Marker | Assay | Reference |
---|---|---|---|---|---|---|---|
Ganciclovir | 2.10 | Low level resistance | Recombinant | Details | Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus. (Jul 2003) | ||
Cidofovir | 5.10 | High level resistance | Recombinant | Details | Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus. (Jul 2003) | ||
Foscarnet | 0.80 | No resistance | Recombinant | Details | Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus. (Jul 2003) |
Mutant | Resistances |
---|---|
L516W |
Ganciclovir:
|
L516W |
Cidofovir:
|
L516W |
Foscarnet:
|