• Since 2014: Full Professor of pharmacology, Faculty of Pharmacy, Limoges.Head of the teaching department of Pharmacology (2 associate prof., 1 study engineer, 1 post-doc) & Hospital Pharmacologist, department of Pharmacology, Toxicology & Pharmacovigilance, Limoges
  • 2006-2014: Associate Professor in medical pharmacology, Faculty of Medicine, Limoges & Hospital Pharmacologist, department of Pharmacology, Toxicology & Pharmacovigilance, Limoges
  • 2005-2006: Hospital pharmacologist, department of Pharmacology and Toxicology, University Hospital of Limoges

Awards

  • 2013-2016: Recipient of the “Prime d’Excellence Scientifique” (PES; personal grant for scientific excellence)

Others

  • Vice-Chair of the IATDMCT pharmacogenetics comitee (International Association of Therapeutic Drug Monitoring & Clinical Toxicology
  • Board member of the French Network for Pharmacogenetics (“RNPGx”) (since 2014)
  • Editorial board member of the Therapeutic Drug Monitoring and Thérapie Journals
  • 2012 & 2014 Professional mobility (6 months) – Department of pharmacokinetics and toxicology (Prof. Bruno Lacarelle) Assistance Publique-Hopitaux de Marseille (AP-HM), Timone Hospital, Marseille, France
  • 2010 French accreditation to supervise research (“Habilitation à Diriger des Recherches”, HDR) Defended on June 16th, 2010 – University of Limoges
  • 2008 Post-doctoral fellow (6 months) – Center for Pharmacogenomics (Prof. Kathleen M Giacomini)
    University of California, San Francisco (UCSF), USA
  • 2005 Ph.D. degree in pharmacology – Laboratory of medical pharmacology (Prof. Pierre Marquet) Faculty of Medicine, University of Limoges, France. Defended on October 19th, 2005
  • 2002 Research master degree in experimental and clinical pharmacology – “Diplôme d’Etude Approfondie” (DEA) Faculty of Medicine, University of Paris XI, Paris, France.
  • 2002 Doctor of Pharmacy, Faculty of Pharmacy, University of Limoges, France
  • 2001 Master of Biological and Medical Sciences, Faculty of Medicine and Pharmacy, Limoges

Supervision

  • Head of a pharmacogenomics group in the research unit 1248 (director Prof. Pierre Marquet) jointly supported by Inserm (National Institute on Health and Medical Research) and the University of Limoges with a strong partnership with the University Hospital of Limoges, France
  • Supervisor or co-supervisor of 9 PhD students (since 2007) and 13 research master students (since 2005)

Teaching – Head of the teaching department of Pharmacology 

  • Pharmaceutical students (2nd, 3rd, 4th and 5th years of study):
    • System pharmacology (nervous system and cardiovascular; inflammation & immune systems, metabolic diseases)
    • Applied pharmacology (drug-drug interactions, prescription analyses, case studies)
    • Pharmacology in drug discovery and development (Regulatory agencies expectations, case studies)

  • Community pharmacists and residents in medicine or pharmacy:
    • Applied pharmacology (drug-drug interactions, pharmacogenetics, case studies)

  • Research masters and post-university courses (Limoges, Paris, Clermont-Ferrand, Tours):
    • Pharmacogenetics
    • Personalized medicine in transplantation
    • Pharmacology in drug discovery and development

Main research interests

  • Pharmacogenetics of immunosuppressants and other treatments in transplantation
  • Implementation of Pharmacogenetics in clinical routine

  • Drugs and xenobiotics disposition in humans

  • Pharmacoepigenetics

  • Next-Generation Sequencing

Experience and Skills

  • Pharmacogenetics: experience includes real time PCR, High Resolution Melting and direct sequencing. IT skills include the design of assay, sequence analysis and haplotype analysis. Clinical association studies and experimental pharmacogenetics.
  • Drug metabolism and transport studies: Experience includes preparation and use of in vitro models (microsomes, recombinant enzymes), design of methods and strategies for identification of metabolites, enzyme, or isoforms involved in a metabolic pathway (either of phase I or phase II), enzyme kinetics, in vitro-in vivo extrapolation and drug-drug interaction studies. Transport studies using caco2, HepaRG. Molecular cloning and cell transfection.
  • Mass spectrometry applied to structural elucidation and determination of small molecules.