Stéphanie Belaiche


Role: Associate Researcher – Clinical Pharmacist, Hospital Practitioner, Lille University Hospital (CHU Lille)

Theme: Pharmacometrics / AI and clinical research

Location: Lille

Email address : 




 

Research

My research project aims to improve personalised care for liver transplant recipients by identifying factors associated with graft rejection during the first year after transplantation. This is a high-risk period during which numerous clinical, biological, pharmacological and behavioural determinants interact.

One of the main lines of this project is to investigate the association between immunosuppressant exposure, its variability, medication adherence and the occurrence of rejection. The objective is to better understand the contribution of each factor, as well as their interactions, to graft outcome.

A second line focuses on how medication adherence evolves during the first-year post-transplantation. Since adherence is a major determinant of transplant success, I aim to better characterize adherence trajectories over time, identify patients at highest risk of non-adherence, and clarify the factors associated with these behaviors. The goal is to better understand how educational interventions can help improve adherence to immunosuppressive therapy and, ultimately, reduce the risk of complications and rejection.

With these data, I intend to develop predictive models integrating clinical, biological, pharmacological and behavioral dimensions, in order to identify at-risk patients and guide personalized interventions. In the longer term, this project is part of a precision medicine approach aimed at optimizing the use of immunosuppressants, strengthening medication adherence and improving outcomes for transplant recipients.

Teaching

  • Faculty of Pharmacy, University of Lille
  • Faculty of Medicine, University of Lille
  • School of Hospital Pharmacy Technicians, Lille

 

Career History

Clinical Pharmacist – Pharmacy Department, Lille

Clinical activity:

  • Hepatogastroenterology Department (Pr Mathurin)
  • Outpatient clinic in the liver transplantation department (Pr Dharancy)
  • Therapeutic patient education in kidney transplantation (Pr Glowacky)
  • 2010–2023: Hospital at Home (Dr Balagny)

Pharmaceutical activity (Pr Odou):

  • Lead clinical pharmacist for solid organ transplantation
  • Lead pharmacist for immunosuppressive and anti-anaemic drugs
2013-2017 PhD (University of Lille): Medication adherence and coefficient of variation of calcineurin inhibitors in kidney transplant recipients.
2013 Hospital Practitioner
2010 PharmD thesis (Lyon): Multidisciplinary management of patients with chronic kidney disease: implementation of a pre-dialysis clinic.

 

Other Information

University Diplomas

2026 University Diploma in Machine Learning in Pharmacology – Dr Labriffe, Pr Woillard, Limoges
2023 Inter-University Diploma in Organ and Tissue Transplantation – Pr Samuel, Paris
2020 University Diploma in Applied Statistics – Pr Pinson, Faculty of Pharmacy, Lille
2008 University Diploma in Clinical Pharmacy – Pr Calop, Grenoble

 

Research Master’s Degree

2005 Master’s in Medicines and Health Products, Pharmacokinetics track – Pr Scherrmann, Paris

 

Training

2024-2025 Training in Bayesian estimation and machine learning – Pr Woillard, Limoges
2025 Clinical examination skills (MED-3): abdominal palpation, digital rectal examination and cardiopulmonary auscultation – PRESAGE simulation centre, Faculty of Medicine, Lille
2025 Therapeutic Patient Education (TPE) Programme Coordinator – ISEFORMSANTE, Lille
2025 Good practice in vaccine prescribing by pharmacists – Pr Carnoy, Lille
2017 Prediction of drug–drug interactions using DDI-Predictor – Pr Tod, Lyon
2016 Face-to-face ICH/GCP clinical trial training
2015 Bone Marrow and Stem Cell Transplantation – University of Washington, Seattle (USA)