Nicolas Picard
Research
My research activities focus on clinical pharmacogenetics, translational pharmacology, and precision medicine. Attached to the Inserm UMR 1248 unit (Pharmacology & Transplantation) since its creation, I previously coordinated the pharmacogenomics research axis (2012–2021). My work centers on translating Next-Generation Sequencing (NGS) and preemptive pharmacogenetic panel strategies into routine clinical care to optimize drug therapy and minimize adverse drug reactions.
Key Research Focuses:
- Organ Transplantation: Implementation of preemptive pharmacogenetic passports and panel analyses to guide immunosuppressive therapy in renal transplant patients.
- Psychiatry & Geriatrics: Clinical trial initiatives evaluating preemptive pharmacogenetic testing in depression management and polymedicated elderly patients admitted for falls.
- Medical Education Research: Impact of innovative pedagogical approaches (e.g., graphic narratives/medical comic books, interprofessional simulation) on student cognitive load and motivation.
Academic Impact & Leadership:
- Scientific Output: Over 100 peer-reviewed articles in international scientific journals (H-index: 29, >3,200 citations).
- Learned Societies: President of the French-Speaking Network of Pharmacogenetics (RNPGx, 2020–2026) and former Secretary-General of the French Society of Pharmacology and Therapeutics (SFPT, 2021–2025).
- Editorial & Advisory Roles: Editorial Board Member for Therapeutic Drug Monitoring and Therapies; Expert Advisor to the French National Authority for Health (HAS) and Biomedicine Agency (ABM).
Teaching
I teach general, applied, and clinical pharmacology across undergraduate, graduate, and post-graduate health programs (Pharmacy, Medicine, Nursing). I serve as Head of the Department of Physiology and Pharmacology at the Faculty of Pharmacy and Academic Coordinator for Hospital Internships (5th year of pharmacy).
Pedagogical Leadership & Innovation:
- Educational Management: Former Assessor to the Dean for Educational Innovation (2020–2024) and UNESS representative for the Faculty of Pharmacy.
- Simulation-Based Education: Founder and Academic Lead of the Pharmaceutical Simulation Center; certified EuSIM simulation instructor. Pioneer in integrating Standardized Patients (SP) and Objective Structured Clinical Examinations (OSCEs/EPOS) in pharmacy curricula.
- Interprofessional Education: Principal Investigator for local implementation of the European Erasmus+ PREP-Team project, establishing cross-disciplinary simulation training for medicine, pharmacy, and nursing students.
- Innovations in Learning: Creator of graphic narrative case studies to reduce cognitive load and enhance student engagement in pharmacology.
Career Path
Degrees & Qualifications
| 2018 | Advanced Preceptor in Health Sciences Education, Universities of Strasbourg & Limoges | |
| 2010 | Habilitation to Direct Research (HDR), University of Limoges | |
| 2003–2005 | PhD in Health Sciences / Biology, University of Limoges | |
| 2001–2002 | MSc (DEA) in Experimental and Clinical Pharmacology, Paris-Sud University | |
| 1996–2002 | Doctor of Pharmacy (PharmD), University of Limoges |
Academic & Clinical Appointments
| 2015–Present | Full Professor & Hospital Pharmacologist (PU-PH), Faculty of Pharmacy & CHU de Limoges | |
| 2006–2014 | Associate Professor & Hospital Pharmacologist (MCU-PH), School of Medicine | |
| 2005–2006 | Contractual Hospital Pharmacologist, CHU de Limoges |
Research Mobility & Visiting Positions
- 2008: Visiting Researcher, University of California San Francisco (UCSF), USA
- 2012, 2014: Visiting Researcher, Timone Hospital (AP-HM), Marseille, France
Other Information
As a licensed clinical biologist, I hold official authorization from the French Biomedicine Agency (ABM) for medical genetic testing. My clinical practice at CHU de Limoges focuses on biological pharmacology and pharmacogenetics:
- Pharmacogenetics Laboratory Operations: Directing specialized pharmacogenetic analyses with an active volume of >600 patient cases annually.
- Tele-expertise : Leader of the first national tele-expertise line for clinical pharmacogenetics in France via Omnidoc.
- National Multidisciplinary Team Meetings (RCP): Co-coordinator of the national multidisciplinary pharmacogenetics meeting (RCPGx), reviewing complex cases and establishing treatment recommendations for clinicians nationwide.
- Hospital Laboratory Responsibilities: Co-lead for Functional Unit 4232 (Oncogenetics, Neurogenetics, and Pharmacogenetics) and validator for routine therapeutic drug monitoring and clinical toxicology (UF 8856).
