CARAT Project in the Spotlight: Article of the month in The Journal of Nuclear Medicine
The CARAT Project article was shortlisted for the cover of the July issue of The Journal of Nuclear Medicine.
The CARAT project “Consortium for Applications in Radio Alpha Therapies”, funded by BPI France, aimed to carry out preclinical studies with 212Pb, in collaboration with the CHU de Limoges and Orano Med on malignant hemopathies.
The proof of concept for the efficacy of 212Pb radioimmunotherapy in a preclinical model of multiple myeloma has been published in a prestigious journal of nuclear medicine. This article has also been selected for the cover of July 2020.
This study in an experimental mouse model mimicking myeloma showed that 212Pb radioimmunotherapy allows tumor regression.
Innovative therapies are needed in the treatment of multiple myeloma where many relapses are still observed despite therapeutic advances.