CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database

W153R

Virus: Human betaherpesvirus 5
Gene: UL27
Resistance summary:*
- Maribavir: No resistance

*If there is more than one line per antiviral, please refer to the table below

Antiviral assays:

Antiviral	EC50 ratio	Phenotype	Strain	Source	Marker	Assay	Reference
Maribavir	1.70	No resistance		Laboratory strain	Recombinant	Details	Diverse cytomegalovirus UL27 mutations adapt to loss of viral UL97 kinase activity under maribavir. (Jan 2009)

Tilloy et al., 2024

Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230