CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    C325W

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Letermovir 9300.00 High level resistance Laboratory strain, Clinical Isolate Recombinant Details New Locus of Drug Resistance in the Human Cytomegalovirus UL56 Gene Revealed by In Vitro Exposure to Letermovir and Ganciclovir. (Sep 2018)

    Mutations at the same locus:

    Mutant Resistances
    C325F Letermovir: High level resistance
    C325R Letermovir: High level resistance
    C325Y Letermovir: High level resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230