CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    L257I

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Letermovir 4.90 Intermediate level resistance Laboratory strain Recombinant Details Rapid In Vitro Evolution of Human Cytomegalovirus UL56 Mutations That Confer Letermovir Resistance. (Oct 2015)

    Mutations at the same locus:

    Mutant Resistances
    L257F Letermovir: High level resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230