CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    L257F

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Letermovir 8.60 High level resistance Laboratory strain Recombinant Details A third component of the human cytomegalovirus terminase complex is involved in letermovir resistance. (Dec 2017)

    Mutations at the same locus:

    Mutant Resistances
    L257I Letermovir: Intermediate level resistance


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230