Herpesvirus Antiviral Resistance
Database


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    V236L

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Letermovir 14.00 High level resistance Laboratory strain Recombinant Details Rapid In Vitro Evolution of Human Cytomegalovirus UL56 Mutations That Confer Letermovir Resistance. (Oct 2015)

    Mutations at the same locus:

    Mutant Resistances
    V236A Letermovir: Low level resistance
    V236M Letermovir: High level resistance