Codex_V5

T821I

Virus: Human betaherpesvirus 5
Gene: UL54
Resistance summary:*
- Ganciclovir: Intermediate level resistance
- Cidofovir: No resistance
- Foscarnet: High level resistance

Antiviral	EC50 ratio	Phenotype	Strain	Source	Marker	Assay	Reference
Ganciclovir	4.50	Intermediate level resistance	N/A	N/A	Recombinant	Details	Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998)
Cidofovir	1.90	No resistance	N/A	N/A	Recombinant	Details	Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998)
Foscarnet	21.00	High level resistance	N/A	N/A	Recombinant	Details	Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998)