CHARMD

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database


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    V781I

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 1.00-4.00 Range of values between No resistance and Intermediate level resistance Recombinant Details Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998)
    Cidofovir 1.20 No resistance Recombinant Details Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998)
    Foscarnet 4.00-5.20 Range of values between Intermediate level resistance and High level resistance Recombinant Details Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. (Jul 1998)


    Tilloy et al., 2024
    Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230