Herpesvirus Antiviral Resistance
Database


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    C539G

    Antiviral assays:

    Antiviral EC50 ratio Phenotype Strain Source Marker Assay Reference
    Ganciclovir 3.10 Intermediate level resistance Recombinant Details Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing. (Aug 2014)
    Cidofovir 4.40 Intermediate level resistance Recombinant Details Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing. (Aug 2014)
    Foscarnet 1.00 No resistance Recombinant Details Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing. (Aug 2014)

    Mutations at the same locus:

    Mutant Resistances
    C539R Ganciclovir: Intermediate level resistance
    C539R Cidofovir: High level resistance
    C539R Foscarnet: No resistance