CHARMD
Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database
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Last update : Mon 20 Apr 2026
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Measure details
Mutant:
E22STOP
Gene:
UL27
Virus:
Human betaherpesvirus 5
Strain:
Reference:
Diverse cytomegalovirus UL27 mutations adapt to loss of viral UL97 kinase activity under maribavir. (Jan 2009)
Antiviral:
Maribavir
EC50 ratio: 2.00
Phenotype: Low level resistance
Passage: N/A
Source: Laboratory strain
Marker: Recombinant
Details:
Yield reduction assay, SEAP
Observations:
No observations associated
Tilloy
et al.
, 2024
Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230