CHARMD

TOP

• Mutant: L600del
• Gene: UL97
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Longitudinal observations on mutations conferring ganciclovir resistance in patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis: The Cytomegalovirus and Viral Resistance Study Group Report Number 8. (Nov 2001)


• Antiviral: Ganciclovir
• EC50 ratio: 1.90
• Phenotype: No resistance
• Passage: N/A
• Source: Laboratory strain, Clinical Isolate
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID : 24903568 11807689 31940472