CHARMD

TOP

• Mutant: L595del
• Gene: UL97
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate. (Feb 1995)


• Antiviral: Ganciclovir
• EC50 ratio: 13.30
• Phenotype: High level resistance
• Passage: N/A
• Source: Laboratory strain, Clinical Isolate
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID : 24903568 11704031 31940472