CHARMD

TOP

• Mutant: L595S
• Gene: UL97
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Ganciclovir and maribavir cross-resistance revisited: Relative drug susceptibilities of canonical cytomegalovirus mutants. (Feb 2024)


• Antiviral: Ganciclovir
• EC50 ratio: 7.50
• Phenotype: High level resistance
• Passage: N/A
• Source: Laboratory strain, Clinical Isolate
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID :udate 2024 9207351, 19063923 24991428 24903568 15230476 11807689 11050017 23985916 18992772 15980340 10968438 23375740 25130511 31940472 Mutation fr?quemment retrouv?e chez les patients re?evant des CS h?matopo?etiques