CHARMD

TOP

• Mutant: A594P
• Gene: UL97
• Virus: Human betaherpesvirus 5
• Strain:
• Reference: Ganciclovir and maribavir cross-resistance revisited: Relative drug susceptibilities of canonical cytomegalovirus mutants. (Feb 2024)


• Antiviral: Maribavir
• EC50 ratio: 1.60
• Phenotype: No resistance
• Passage: N/A
• Source: Laboratory strain, Clinical Isolate
• Marker: Recombinant


• Details:
  • PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer


• Observations:
  • Autre publi ID : 19063923 24903568 12198609 20961907 23668613 11750939 Mutation frequemment retrouvee chez les patients recevant des CS hématopoietiques