CHARMD
Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database
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Last update : Mon 20 Apr 2026
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Measure details
Mutant:
T813S
Gene:
UL54
Virus:
Human betaherpesvirus 5
Strain:
Reference:
Growth and drug resistance phenotypes resulting from cytomegalovirus DNA polymerase region III mutations observed in clinical specimens. (Nov 2007)
Antiviral:
Foscarnet
EC50 ratio: 4.90
Phenotype: Intermediate level resistance
Passage: N/A
Source: N/A
Marker: Recombinant
Details:
PRA, ELISA tests, flow cytometry and DNA-DNA hybridization assays, quantitative real-time PCR, reporter cell lines, polymerase biochemical assays, marker transfer
Observations:
No observations associated
Tilloy
et al.
, 2024
Interdeposit Digital Number: IDDN.FR.001.420004.000.S.X.2024.000.31230